小鼠抗MADCAM1单克隆抗体

Background:

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].

Applications:

WB

Name of antibody:

MADCAM1

Immunogen:

Fusion protein of human MADCAM1

Full name:

mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 1

Synonyms:

MACAM1

SwissProt:

Q13477

WB Predicted band size:

40 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000