兔抗BAG4多克隆抗体

Background:

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling.

Applications:

ELISA, WB

Name of antibody:

BAG4

Immunogen:

Synthetic peptide of human BAG4

Full name:

BCL2-associated athanogene 4

Synonyms：

SODD; BAG-4

SwissProt:

O95429

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

50 kDa

WB Positive control:

Human normal stomach tissue

WB Recommended dilution:

200-1000