小鼠抗PROM1单克隆抗体

Background:

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

PROM1

Immunogen:

Fusion protein of human PROM1

Full name:

prominin 1

Synonyms:

RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061

SwissProt:

O43490

WB Predicted band size:

97 kDa

WB Positive control:

CaCo2 cell lysate

WB Recommended dilution:

1000-5000