小鼠抗IQGAP1单克隆抗体

Background:

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Applications:

WB, IHC

Name of antibody:

IQGAP1

Immunogen:

Fusion protein of human IQGAP1

Full name:

IQ motif containing GTPase activating protein 1

Synonyms:

SAR1; p195; HUMORFA01

SwissProt:

P46940

IHC positive control:

Human colorectal cancer and Human pancreas tissue

IHC Recommend dilution:

500-2000

WB Predicted band size:

189 KD

WB Positive control:

Hela, 293T, Jurkat, MCF7, K562, A549, HepG2 cell lysates

WB Recommended dilution:

500-2000