兔抗PTRH2多克隆抗体

Background:

PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.

Applications:

ELISA, WB, IHC

Name of antibody:

PTRH2

Immunogen:

Fusion protein of human PTRH2

Full name:

peptidyl-tRNA hydrolase 2

Synonyms：

BIT1; PTH2; CFAP37; CGI-147

SwissProt:

Q9Y3E5

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

19 kDa

WB Positive control:

Raji, Jurkat, 231, hepg2 and K562 cells

WB Recommended dilution:

1000-5000