小鼠抗HTRA2单克隆抗体

Background:

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Applications:

WB, IP

Name of antibody:

HTRA2

Immunogen:

Fusion protein of human HTRA2

Full name:

HtrA serine peptidase 2

Synonyms:

OMI; MGCA8; PARK13; PRSS25

SwissProt:

O43464

WB Predicted band size:

49 kDa

WB Positive control:

293T cell lysate

WB Recommended dilution:

500-2000