小鼠抗HSPD1单克隆抗体

Background:

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Applications:

WB, IF, IP

Name of antibody:

HSPD1

Immunogen:

Fusion protein of human HSPD1

Full name:

heat shock protein family D (Hsp60) member 1

Synonyms:

HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60

SwissProt:

P10809

WB Predicted band size:

61 kDa

WB Positive control:

3T3, C2C12, C6, Jurkat, Raji and Hela cell lysates

WB Recommended dilution:

1000-5000

IF positive control:

Hela cells

IF Recommend dilution:

50-100