小鼠抗HK1单克隆抗体

Background:

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Applications:

WB

Name of antibody:

HK1

Immunogen:

Fusion protein of human HK1

Full name:

hexokinase 1

Synonyms:

HK; HKD; HKI; HXK1; RP79; HMSNR; HK1-ta; HK1-tb; HK1-tc; hexokinase

SwissProt:

P19367

WB Predicted band size:

102 kDa

WB Positive control:

MCF7, Jurkat, CHO-K1, C2C12, C6, 3T3 and Hela cell lysates

WB Recommended dilution:

1000-5000