小鼠抗HK2单克隆抗体

Background:

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways.This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Applications:

WB, IF, FC

Name of antibody:

HK2

Immunogen:

Fusion protein of human HK2

Full name:

hexokinase 2 (HK2)

Synonyms:

HKII; HXK2

SwissProt:

P52789

WB Predicted band size:

102 kDa

WB Positive control:

HepG2, Hela, HT-29, MDCK cell lysates

WB Recommended dilution:

500-2000