兔抗DTWD1多克隆抗体

Background:

Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Applications:

ELISA, IHC

Name of antibody:

DTWD1

Immunogen:

Full length fusion protein

Full name:

DTW domain containing 1

Synonyms：

MDS009

SwissProt:

Q8N5C7

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human colorectal cancer

IHC Recommend dilution:

20-100