小鼠抗HAVCR2单克隆抗体

Background:

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011].

Applications:

IHC

Name of antibody:

HAVCR2

Immunogen:

Fusion protein of human HAVCR2

Full name:

hepatitis A virus cellular receptor 2 (HAVCR2)

Synonyms:

HAVcr-2; KIM-3; Tim-3; TIM3; TIMD-3; TIMD3

SwissProt:

Q8TDQ0

IHC positive control:

adenocarcinoma of human breast tissue and human Kidney tissue andhuman pancreas tissue and adenocarcinoma of human endometrium tissue

IHC Recommend dilution:

30-150