兔抗C3 (βchain)多克隆抗体

Background:

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Applications:

ELISA, WB

Name of antibody:

C3 (β chain)

Immunogen:

Synthetic peptide of human C3 (β chain)

Full name:

complement component 3 (β chain)

Synonyms：

ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1

SwissProt:

P01024

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

70 kDa

WB Positive control:

Human serum

WB Recommended dilution:

200-1000