兔抗PNPLA6多克隆抗体

Background:

This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

PNPLA6

Immunogen:

Synthesized peptide derived from internal of human PNPLA6.

Full name:

patatin-like phospholipase domain containing 6

Synonyms：

NTE; sws; BNHS; SPG39; NTEMND; iPLA2delta

SwissProt:

Q8IY17

WB Predicted band size:

150 kDa

WB Positive control:

COLO205 cells lysate

WB Recommended dilution:

500-3000