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021-54845833/15800441009
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Background: |
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. |
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Applications: |
WB |
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Name of antibody: |
IL2RB(Phospho-Tyr364) |
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Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 364(Q-G-Y(p)-F-F) derived from Human IL-2Rβ/CD122 . |
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Full name: |
interleukin 2 receptor, beta |
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Synonyms： |
CD122; IL15RB; P70-75 |
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SwissProt: |
P14784 |
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WB Predicted band size: |
61 kDa |
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WB Positive control: |
COS7 cells lysates |
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WB Recommended dilution: |
500-1000 |
