小鼠抗HADHA单克隆抗体

Background:

This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

Applications:

WB

Name of antibody:

HADHA

Immunogen:

Fusion protein of human HADHA

Full name:

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

Synonyms:

GBP; ECHA; HADH; LCEH; MTPA; LCHAD; TP-ALPHA

SwissProt:

P40939

WB Predicted band size:

83 KD

WB Positive control:

HepG2 cell, Rat heart tissue lysates

WB Recommended dilution:

200-1000