兔抗ATN1多克隆抗体

Background:

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Applications:

ELISA, IHC

Name of antibody:

ATN1

Immunogen:

Synthetic peptide of human ATN1

Full name:

atrophin 1

Synonyms:

B37; HRS; NOD; DRPLA; D12S755E

SwissProt:

P54259

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human ovarian cancer

IHC Recommend dilution:

40-200