小鼠抗GSK3B单克隆抗体

Background:

The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.

Applications:

WB, IHC

Name of antibody:

GSK3B

Immunogen:

Fusion protein of human GSK3B

Full name:

glycogen synthase kinase 3 beta

SwissProt:

P49841

IHC positive control:

Human tonsil and Human colorectal cancer; Human esophagus cancer

IHC Recommend dilution:

100-500

WB Predicted band size:

47 kDa

WB Positive control:

293T, Hela cell, Mouse brain tissue lysates

WB Recommended dilution:

1000-5000