小鼠抗MTOR单克隆抗体

Background:

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Applications:

WB, IHC

Name of antibody:

MTOR

Immunogen:

Fusion protein of human MTOR

Full name:

mechanistic target of rapamycin (serine/threonine kinase) (MTOR)

Synonyms:

FRAP; FRAP1; FRAP2; RAFT1; RAPT1

SwissProt:

P42345

IHC positive control:

carcinoma of human liver tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

289 kDa

WB Positive control:

Hela, Jurkat, A431, MCF7 cell, Rat testis tissue, Rat brain tissue and 293T cell lysates

WB Recommended dilution:

500-2000