小鼠抗GZMB单克隆抗体

Background:

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC, IF

Name of antibody:

GZMB

Immunogen:

Fusion protein of human GZMB

Full name:

granzyme B (GZMB)

Synonyms:

HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1

SwissProt:

P10144

IHC positive control:

adenocarcinoma of human endometrium tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

28 kDa

WB Positive control:

SVT2, A549, MCF7 cell lysates

WB Recommended dilution:

200-1000