小鼠抗LRRFIP1单克隆抗体

Background:

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

Applications:

WB

Name of antibody:

LRRFIP1

Immunogen:

Fusion protein of human LRRFIP1

Full name:

LRR binding FLII interacting protein 1

Synonyms:

GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1

SwissProt:

Q32MZ4

WB Predicted band size:

89 kDa

WB Positive control:

Raji, C2C12, MCF7 and Jurkat cell lysates

WB Recommended dilution:

1000-5000