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Background: |
Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids. |
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Applications: |
WB, IHC |
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Name of antibody: |
CYP8B1 |
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Immunogen: |
Synthesized peptide derived from internal of human Cytochrome P450 8B1. |
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Full name: |
cytochrome P450, family 8, subfamily B, polypeptide 1 |
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Synonyms： |
CP8B; CYP12 |
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SwissProt: |
Q9UNU6 |
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IHC positive control: |
Human liver carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
293 cells lysate |
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WB Recommended dilution: |
500-3000 |
