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中文名称 : 小鼠抗CCT8L2单克隆抗体
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Background: |
CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
CCT8L2 |
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Immunogen: |
Fusion protein of human CCT8L2 |
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Full name: |
chaperonin containing TCP1, subunit 8 (theta)-like 2 (CCT8L2) |
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Synonyms: |
CESK1 |
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SwissProt: |
Q96SF2 |
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IHC positive control: |
human colon tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
59 kDa |
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WB Positive control: |
A549, MCF-7 cell lysates |
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WB Recommended dilution: |
200-1000 |
