兔抗CENPC多克隆抗体

Background:

Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.

Applications:

ELISA, IHC

Name of antibody:

CENPC

Immunogen:

Fusion protein of human CENPC

Full name:

centromere protein C

Synonyms：

MIF2; hcp-4; CENP-C; CENPC1

SwissProt:

Q03188

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human prostate cancer and Human esophagus cancer

IHC Recommend dilution:

50-200