兔抗CELF1多克隆抗体

Background:

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

WB

Name of antibody:

CELF1

Immunogen:

Synthesized peptide derived from internal of human CELF-1.

Full name:

CUGBP, Elav-like family member 1

Synonyms：

CUGBP; NAB50; NAPOR; CUG-BP; CUGBP1; hNab50; BRUNOL2; EDEN-BP

SwissProt:

Q92879

WB Predicted band size:

52 kDa

WB Positive control:

Hela cells and HepG2 cells lysates

WB Recommended dilution:

500-3000