小鼠抗BID单克隆抗体

Background:

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC, IF

Name of antibody:

BID

Immunogen:

Fusion protein of human BID

Full name:

BH3 interacting domain death agonist (BID), transcript variant 2

Synonyms:

FP497

SwissProt:

P55957

IHC positive control:

human pancreas tissue and adenocarcinoma of human endometrium tissue; human liver tissue and carcinoma of human liver tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

22 kDa

WB Positive control:

HepG2, Hela, A549, Jurkat, MCF-7 cell lysates

WB Recommended dilution:

500-2000