小鼠抗S100A6单克隆抗体

Background:

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Applications:

WB

Name of antibody:

S100A6

Immunogen:

Fusion protein of human S100A6

Full name:

S100 calcium binding protein A6

Synonyms:

2A9; PRA; 5B10; CABP; CACY

SwissProt:

P06703

WB Predicted band size:

10 kDa

WB Positive control:

COS7, MCF7, HCT116 and A549 cell lysates

WB Recommended dilution:

1000-5000