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Background: |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. |
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Applications: |
WB |
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Name of antibody: |
S100A6 |
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Immunogen: |
Fusion protein of human S100A6 |
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Full name: |
S100 calcium binding protein A6 |
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Synonyms: |
2A9; PRA; 5B10; CABP; CACY |
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SwissProt: |
P06703 |
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WB Predicted band size: |
10 kDa |
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WB Positive control: |
COS7, MCF7, HCT116 and A549 cell lysates |
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WB Recommended dilution: |
1000-5000 |
