小鼠抗BIRC3单克隆抗体

Background:

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011].

Applications:

WB, FC

Name of antibody:

BIRC3

Immunogen:

Fusion protein of human BIRC3

Full name:

baculoviral IAP repeat containing 3 (BIRC3), transcript variant 1

Synonyms:

AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49

SwissProt:

Q13489

WB Predicted band size:

68 kDa

WB Positive control:

HepG2, Hela, A549, Jurkat, MCF-7 cell lysates

WB Recommended dilution:

200-1000