兔抗BRI3BP多克隆抗体

Background:

BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.

Applications:

ELISA, WB, IHC

Name of antibody:

BRI3BP

Immunogen:

Synthetic peptide of human BRI3BP

Full name:

BRI3 binding protein

Synonyms：

KG19; BNAS1; HCCR-1; HCCR-2; HCCRBP-1

SwissProt:

Q8WY22

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human tonsil

IHC Recommend dilution:

25-100

WB Predicted band size:

28 kDa

WB Positive control:

K562 cell，Mouse brain tissue and RAW264.7 cell

WB Recommended dilution:

200-1000