兔抗CHRM1多克隆抗体

Background:

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13

Applications:

ELISA, WB

Name of antibody:

CHRM1

Immunogen:

Fusion protein of human CHRM1

Full name:

cholinergic receptor, muscarinic 1

Synonyms：

M1; HM1; M1R

SwissProt:

P11229

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

51 kDa

WB Positive control:

Mouse brain tissue

WB Recommended dilution:

200-1000