兔抗CD3E多克隆抗体

Background:

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Applications:

WB

Name of antibody:

CD3E

Immunogen:

Synthetic peptide of human CD3E

Full name:

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms：

T3E; TCRE; FLJ18683

SwissProt:

P07766

WB Predicted band size:

23 kDa

WB Positive control:

Molt4 and Jurkat cells

WB Recommended dilution:

500-1000