小鼠抗ENO1单克隆抗体

Background:

This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.

Applications:

WB

Name of antibody:

ENO1

Immunogen:

Fusion protein of human ENO1

Full name:

enolase 1

Synonyms:

NNE; PPH; MPB1; ENO1L1; HEL-S-17

SwissProt:

P06733

WB Predicted band size:

47 kDa

WB Positive control:

T47D, 3T3, COS7, C6 and Hela cell lysates

WB Recommended dilution:

1000-5000