兔抗CD2AP多克隆抗体

Background:

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Applications:

ELISA, WB, IHC

Name of antibody:

CD2AP

Immunogen:

Synthetic peptide of human CD2AP

Full name:

CD2-associated protein

Synonyms：

CMS

SwissProt:

Q9Y5K6

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human Lymphoma and Human liver cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

71 kDa

WB Positive control:

A431 and Raji cells

WB Recommended dilution:

1000-5000