兔抗ESRRG多克隆抗体

Background:

This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways.

Applications:

ELISA, WB, IHC

Name of antibody:

ESRRG

Immunogen:

Fusion protein of human ESRRG

Full name:

estrogen-related receptor gamma

Synonyms:

ERR3; NR3B3; ERRgamma

SwissProt:

P62508

IHC positive control:

Human gastric cancer and human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

51 kDa

WB Positive control:

Mouse lung tissue

WB Recommended dilution:

500-2000