兔抗CNTFR多克隆抗体

Background:

This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

CNTFR

Immunogen:

Synthetic peptide of human CNTFR

Full name:

ciliary neurotrophic factor receptor

SwissProt:

P26992

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

41 kDa

WB Positive control:

Mouse heart tissue lysate

WB Recommended dilution:

500-2000