兔抗CCR5(Phospho-Ser349) 多克隆抗体

Background:

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES).

Applications:

WB

Name of antibody:

CCR5(Phospho-Ser349)

Immunogen:

Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5.

Full name:

chemokine (C-C motif) receptor 5 (gene/pseudogene)

Synonyms：

CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5

SwissProt:

P51681

WB Predicted band size:

41 kDa

WB Positive control:

A549 cells lysates

WB Recommended dilution:

500-1000