兔抗CCDC106多克隆抗体

Background:

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.

Applications:

ELISA, IHC

Name of antibody:

CCDC106

Immunogen:

Fusion protein of human CCDC106

Full name:

coiled-coil domain containing 106

Synonyms：

ZNF581; HSU79303

SwissProt:

Q9BWC9

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human cervical cancer and human colon cancer

IHC Recommend dilution:

100-300