兔抗OCLN多克隆抗体

Background:

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

Applications:

ELISA, IHC

Name of antibody:

OCLN

Immunogen:

Fusion protein of human OCLN

Full name:

Occludin

Synonyms：

BLCPMG

SwissProt:

Q16625

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colon cancer and Human lung cancer

IHC Recommend dilution:

15-50