兔抗OCRL多克隆抗体

Background:

This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

OCRL

Immunogen:

Synthetic peptide of human OCRL

Full name:

OCRL, inositol polyphosphate-5-phosphatase

Synonyms:

LOCR; NPHL2; OCRL1; INPP5F; OCRL-1

SwissProt:

Q01968

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100