兔抗C15orf40多克隆抗体

Background:

Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. The C15orf40 gene product has been provisionally designated C15orf40 pending further characterization.

Applications:

ELISA, WB, IHC

Name of antibody:

C15orf40

Immunogen:

Fusion protein of human C15orf40

Full name:

chromosome 15 open reading frame 40

SwissProt:

Q8WUR7

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

25-100

WB Predicted band size:

16 kDa

WB Positive control:

Human heart tissue lysate

WB Recommended dilution:

500-2000