兔抗AFDN多克隆抗体

Background:

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.

Applications:

ELISA, IHC

Name of antibody:

AFDN

Immunogen:

Synthetic peptide of human AFDN

Full name:

afadin, adherens junction formation factor

Synonyms:

AF6; MLLT4; MLL-AF6; l-afadin

SwissProt:

P55196

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and Human thyroid cancer

IHC Recommend dilution:

25-100