兔抗C12orf10多克隆抗体

Background:

C12orf10, also known as MYG1, MYG1 is a 376 amino acid nucleo-mitochondrial protein belonging to the UPF0160 (MYG1) family. MYG1 is encoded by a gene that maps to human chromosome 12q13.13 and is ubiquitously expressed in simple as well as complex eukaryotes, with highest levels in testis. Considered to have a metal-dependent protein hydrolase (UPF0160) domain, MYG1 exhibits a mitochondrial targeting signal in the N-terminal region and a Pat7-type nuclear localization signal in the region between amino acids 33-39. Although MYG1 displays differential patterns and levels of expression during embryonic development, expression in normal adult tissues is stable, suggesting MYG1 involvement in early developmental processes and in adult stress/illness conditions. Elevation of MYG1 expression may be also associated with vitiligo susceptibility.

Applications:

ELISA, WB, IHC

Name of antibody:

C12orf10

Immunogen:

Fusion protein of human C12orf10

Full name:

chromosome 12 open reading frame 10

Synonyms:

MYG; MYG1; Gamm1; MST024; MSTP024

SwissProt:

Q9HB07

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer;

IHC Recommend dilution:

20-100

WB Predicted band size:

42 kDa

WB Positive control:

293T,MCF-7 and PC-3 cell lysates

WB Recommended dilution:

200-1000