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Background: |
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
EPHB3 |
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Immunogen: |
Synthetic peptide of human EPHB3 |
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Full name: |
EPH receptor B3 |
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Synonyms： |
ETK2; HEK2; TYRO6 |
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SwissProt: |
P54753 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
