兔抗BMF多克隆抗体

Background:

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications:

ELISA, WB, IHC

Name of antibody:

BMF

Immunogen:

Synthetic peptide of human BMF

Full name:

Bcl2 modifying factor

SwissProt:

Q96LC9

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human gastric cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

20 kDa

WB Positive control:

293T cell lysate

WB Recommended dilution:

500-2000