兔抗BMI1多克隆抗体

Background:

BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Applications:

ELISA, WB

Name of antibody:

BMI1

Immunogen:

Fusion protein of human BMI1

Full name:

BMI1 polycomb ring finger oncogene

Synonyms：

PCGF4; RNF51; FLVI2/BMI1

SwissProt:

P35226

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

37 kDa

WB Positive control:

231 and A549 cells, hela cells and mouse brain tissue

WB Recommended dilution:

200-1000