兔抗CENPF多克隆抗体

Background:

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Applications:

ELISA, IHC

Name of antibody:

CENPF

Immunogen:

Synthetic peptide of human CENPF

Full name:

centromere protein F

Synonyms:

CENF; hcp-1; CILD31; PRO1779

SwissProt:

P49454

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain and human lung cancer

IHC Recommend dilution:

30-150