兔抗BLK(Phospho-Tyr501)多克隆抗体

Background:

This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.

Applications:

IHC

Name of antibody:

BLK(Phospho-Tyr501)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK.

Full name:

BLK proto-oncogene, Src family tyrosine kinase

Synonyms：

MODY11

SwissProt:

P51451

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100