兔抗UBXN1多克隆抗体

Background:

Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

Applications:

ELISA, WB, IHC

Name of antibody:

UBXN1

Immunogen:

Full length fusion protein

Full name:

UBX domain protein 1

Synonyms:

2B28; SAKS1; UBXD10

SwissProt:

Q04323

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human cervical cancer

IHC Recommend dilution:

40-200

WB Predicted band size:

33 kDa

WB Positive control:

Mouse brain tissue，Hela and HEPG2 cell lysates

WB Recommended dilution:

500-2000