兔抗BIRC7多克隆抗体

Background:

This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants

Applications:

ELISA, IHC

Name of antibody:

BIRC7

Immunogen:

Synthetic peptide of human BIRC7

Full name:

baculoviral IAP repeat containing 7

Synonyms：

KIAP; LIVIN; MLIAP; RNF50; ML-IAP

SwissProt:

Q96CA5

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human gastric cancer and human tonsil

IHC Recommend dilution:

25-100