兔抗BCL7A多克隆抗体

Background:

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

BCL7A

Immunogen:

Synthesized peptide derived from internal of human BCL7A.

Full name:

B-cell CLL/lymphoma 7A

Synonyms：

BCL7

SwissProt:

Q4VC05

WB Predicted band size:

23 kDa

WB Positive control:

Huvec cells lysate

WB Recommended dilution:

500-3000