兔抗CTSE多克隆抗体

Background:

The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

CTSE

Immunogen:

Fusion protein of human CTSE

Full name:

Cathepsin E

Synonyms：

CATE

SwissProt:

P14091

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human ovarian cancer and Human liver cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

43 kDa

WB Positive control:

Mouse stomach tissue

WB Recommended dilution:

500-2000